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AN INVESTIGATION OF THE ASSOCIATION BETWEEN BLOOD GROUP TYPES AND SUSCEPTIBILITY TO BACTERIAL INFECTIONS IN DIABETIC PATIENTS AT FEDERAL UNIVERSITY TEACHING HOSPITAL, OWERRI

Abstract

This study investigates the potential association between blood group types and susceptibility to bacterial infections in diabetic patients at the Federal University Teaching Hospital, Owerri. Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood sugar levels, which can weaken the immune system and increase susceptibility to infections. Bacterial infections are common complications of diabetes and can lead to severe health consequences if not promptly treated.

The study aims to determine whether specific blood group types are more prone to bacterial infections among diabetic patients. By analyzing medical records and conducting microbiological tests on bacterial isolates from diabetic patients with different blood group types, the research seeks to elucidate any significant correlations between blood group types and susceptibility to bacterial infections.

The findings of this study have implications for clinical practice and public health interventions. If certain blood group types are found to be associated with a higher risk of bacterial infections in diabetic patients, healthcare providers can tailor preventive measures and treatment strategies accordingly. Moreover, understanding the underlying factors contributing to increased susceptibility to infections in diabetic patients with specific blood group types can inform targeted interventions to improve patient outcomes and reduce the burden of infections in this population.

Overall, this study contributes to the existing body of knowledge on the interaction between diabetes, blood group types, and bacterial infections. By identifying potential risk factors and elucidating the mechanisms underlying susceptibility to infections, the research aims to support evidence-based strategies for the management and prevention of bacterial infections in diabetic patients.

Table of Contents

Chapter One: Introduction

1.1 Background of the Study

1.2 Statement of the Problem

1.3 Objectives of the Study

1.4 Research Questions

1.5 Hypotheses

1.6 Significance of the Study

1.7 Scope and Limitations

1.8 Definition of Key Terms

Chapter Two: Literature Review

2.1 Introduction

2.2 Overview of Diabetes Mellitus

2.2.1 Types of Diabetes

2.2.2 Complications of Diabetes

2.3 Blood Group Systems

2.3.1 ABO Blood Group System

2.3.2 Rh Blood Group System

2.4 Bacterial Infections in Diabetic Patients

2.4.1 Common Bacterial Infections

2.4.2 Mechanisms of Increased Susceptibility

2.5 Relationship Between Blood Group and Susceptibility to Infections

2.6 Summary of Literature Review

Chapter Three: Methodology

3.1 Introduction

3.2 Research Design

3.3 Study Area

3.4 Population and Sample

3.4.1 Inclusion and Exclusion Criteria

3.5 Data Collection Methods

3.5.1 Medical Records Analysis

3.5.2 Laboratory Tests and Microbiological Analysis

3.6 Data Analysis Techniques

3.7 Ethical Considerations

3.8 Limitations of the Methodology

Chapter Four: Analysis and Discussion

4.1 Introduction

4.2 Demographic Characteristics of the Study Population

4.3 Distribution of Blood Group Types Among Diabetic Patients

4.4 Incidence of Bacterial Infections in Diabetic Patients

4.5 Association Between Blood Group Types and Bacterial Infections

4.5.1 Analysis of Blood Group A and Susceptibility

4.5.2 Analysis of Blood Group B and Susceptibility

4.5.3 Analysis of Blood Group AB and Susceptibility

4.5.4 Analysis of Blood Group O and Susceptibility

4.6 Discussion of Findings

4.6.1 Comparison with Existing Literature

4.6.2 Implications for Clinical Practice

4.7 Summary of Analysis

Chapter Five: Conclusion and Recommendations

5.1 Introduction

5.2 Summary of Findings

5.3 Conclusion

5.4 Recommendations

5.4.1 Recommendations for Healthcare Providers

5.4.2 Recommendations for Patients

5.4.3 Policy Recommendations

5.5 Recommendations for Further Research

5.6 Conclusion

References

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