ESTRADIOL AND CHOLESTEROL LEVEL AMONG FEMALES WITH POLYCYSTIC OVARIAN SYNDROME IN RIVERS STATE

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ESTRADIOL AND CHOLESTEROL LEVEL AMONG FEMALES WITH POLYCYSTIC OVARIAN SYNDROME IN RIVERS STATE

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disease in women, characterized by heterogeneous presentation of hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology (PCOM). This study was carried out to assess plasma levels of cholesterol and estradiol among female with polycystic ovarian syndrome (PCOs). Forty clinically diagnosed polycystic ovarian syndrome (PCOs) in the period between February to May 2017,were chosen randomly from Alsir Abu Hassan Center for Fertility in Rivers State, and forty apparently healthy individuals as control group, to evaluate the plasma levels of cholesterol and estradiol .Plasma estradiol was measured by using ELISA machine and cholesterol measured by BS-380 chemistry analyzer and results were analyzed using Statistical Package for Social Science (SPSS), computer programmed version 11.5. Anti-Müllerian hormone (AMH) used for the diagnosis of PCOs and when it is levels in the patients compared to the control group. (Mean±SD: 10.6±5.92 versus 1.4±0.22) ng/ml respectively with P.Value 0.000. The study showed that, the mean plasma levels of cholesterol was significantly increased in PCOs female patients. (Mean±SD: 207.6±33.4 versus112±33.4 mmoL /L) respectively with P.vale 0.000.

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